This study aimed to investigate the catch composition, length frequency, fishing effort and distribution of Sepia pharaonis caught by pot in the fishing grounds of Ramin and Konarak (Sistan and Baluchestan Province). During October, November, December, and January 2021, 387 specimens were collected in depths of 20 to 40 meters in Ramin and 368 specimens were collected in Konarak. In the Ramin region, the highest number (129 specimens) and the highest range of length (17.3-40.6cm) and weight (367.3-3847.5g) were observed in January. The highest number of squids caught belonged to the length class of 24.8-27.2cm (54 specimens) and the lowest number belonged to the length class 39.8-42.2cm (2 specimens). In the Konarak region, the highest number was observed in January (113 specimens), and the highest ranges of length (18.2-41.2cm) and weight (426.17-3886.24g) were observed in October. The highest number of caught squid belonged to the length class of 29.3-32cm (49 specimens) and the lowest number belonged to the length class of 39.9-42.4cm (6 specimens). In the Ramin region showed that 14 species were caught in October, 11 species in November, 14 species in December and 16 species in January. Also, in Konarak, 16 species were caught in October, 15 species in November, 13 species in December and 16 species in January. The values of a, b and R2 parameters of length and weight, in the Ramin region, were 0.2085, 2.6422, and 0.9791, respectively. The values of a, b and R2 parameters of length and weight, in Konarak, were 0.17038, 2.6962, and 0.9842 respectively. Comparison of CPUE values showed that the highest values in these two regions were observed in January and the lowest values were observed in October. The results of this study have enhanced comprehension of the population dynamics of Sepia pharaonis in these fishing grounds and provide valuable insights into the ecological conditions of the studied areas.